Ovarian rejuvenation therapy is a new and innovative approach to enhancing fertility. It is often carried out using platelet-rich plasma (PRP) or stem cell therapy.
Ovarian Rejuvenation with Stem cells is also called Autologous Stem Cell Transplant in the Ovary (ASCOT). These cells are undifferentiated cells that have the ability to develop into different types of cells, including ovarian cells.
This treatment has the potential to help women with a variety of fertility problems, including premature ovarian failure, low ovarian reserve, and cancer-related infertility.
Purpose of Ovarian Rejuvenation Techniques
The primary goal of ovarian rejuvenation is to improve the quality and quantity of a woman’s eggs, potentially improving fertility. It may also delay the onset of menopause and alleviate symptoms associated with ovarian ageing.
This therapy is specifically introduced in order to ensure that the patient is able to become pregnant with their own eggs.
Step by Step Process of Ovarian Rejuvenation Therapy
Consultation & Evaluation :-
The first step in the ovarian rejuvenation process is a comprehensive consultation and evaluation with a fertility specialist in your area.
This typically involves a review of your medical history, a discussion of your fertility goals, and possibly some diagnostic tests.
Extraction :-
In PRP therapy, the actual procedure begins with the extraction of blood from the patient. This blood is then used to prepare the Platelet-Rich Plasma (PRP).
In stem cell therapy, stem cells can be extracted from various sources, such as the patient’s own bone marrow or adipose tissue. This involves a surgical procedure under anesthesia.
Preparation :-
In PRP therapy, the extracted blood is then processed in a centrifuge to separate the platelets and plasma from the other blood components.
The result is platelet-rich plasma (PRP), which is rich in growth factors that can stimulate tissue regeneration. In stem cell therapy, the extracted stem cells are separated and prepared for transplantation.
Some procedures may also involve mechanically fragmenting the ovarian cortex into small pieces
Transplantation :-
In PRP therapy, the prepared PRP is then injected directly into the ovaries.
In Stem Cell therapy, the prepared stem cells are then injected into the ovary using a specialized technique of laparoscopic surgery where the angulation of the needle has to be absolutely perfect to the ovarian cortex.
For this procedure, stem cells are extracted from the ovary by a simple bone marrow aspiration needle.
This procedure is carried out by an orthopaedic surgeon who specializes in bone marrow aspiration. It is believed that theca stem cells, which are present in the ovary, might be the most beneficial stem cells.
However, culture growth extraction and multiplication of these stem cells is currently under research phase.
Post-Procedure Care :-
After the procedure, patients are monitored closely to evaluate the effectiveness of the treatment and manage any potential side effects
Follow-up & Monitoring :-
Regular follow-ups are essential to monitor changes in menstrual patterns, hormone levels, and other indicators of improved ovarian function
Ovarian rejuvenation therapy is a promising new treatment, but it is still considered experimental and may not be suitable for everyone. It is important to consult with a trusted fertility specialist in Mumbai or other cities in India before considering this treatment.